Hampered by historical paradigms--echinocandins and the treatment of Candida endocarditis

Mycoses. 2014 May;57(5):316-9. doi: 10.1111/myc.12154. Epub 2013 Nov 20.

Abstract

Infective endocarditis due to Candida sp. has a high mortality rate. Traditionally, management involves early surgery and prolonged amphotericin ± flucytosine. We report a case of Candida parapsilosis bileaflet mitral valve endocarditis cured with anidulafungin and fluconazole, and review the role of echinocandins in the management of Candida endocarditis.

Keywords: Candida; anidulafungin; echinocandin; endocarditis.

Publication types

  • Case Reports

MeSH terms

  • Anidulafungin
  • Antifungal Agents / therapeutic use*
  • Candida / isolation & purification*
  • Candida / physiology
  • Echinocandins / therapeutic use
  • Endocarditis / drug therapy*
  • Endocarditis / microbiology*
  • Fluconazole / therapeutic use
  • Humans
  • Male
  • Middle Aged

Substances

  • Antifungal Agents
  • Echinocandins
  • Fluconazole
  • Anidulafungin