Hypersensitivity to titanium: a less explored area of research

J Indian Prosthodont Soc. 2012 Dec;12(4):201-7. doi: 10.1007/s13191-012-0139-4. Epub 2012 Jul 13.

Abstract

Titanium is considered as an excellent biocompatible metal and it is used in implant dentistry. Literature suggests that Ti can induce clinically relevant hypersensitivity and other immune dysfunctions in certain patients chronically exposed to this reactive metal. At the same time, no standard patch test for Ti has so far been developed, and positive reactions to Ti have therefore only rarely been demonstrated with skin testing. This article reports about the corrosion of dental implants, their significance when hypersensitivity is present, and the literature available till date regarding hypersensitivity of titanium.

Keywords: Corrosion; Hypersensitivity tests; Inflammatory reaction; Titanium.

Publication types

  • Review