[An iris metastasis revealed a bronchopulmonary cancer]

J Fr Ophtalmol. 2014 Feb;37(2):125-9. doi: 10.1016/j.jfo.2013.05.012. Epub 2014 Jan 31.
[Article in French]

Abstract

We report the case of a 53-year-old patient referred by his ophthalmologist for a red, painful eye. On exam, he demonstrated findings of granulomatous uveitis with ocular hypertension (38 mm Hg) and a whitish, vascularized iris tumor with invasion of the irido-corneal angle. As our first hypothesis was an iris metastasis, a systemic work-up was carried out, which revealed moderately differentiated broncho-pulmonary carcinoma with multiple metastases (brain, cerebellum and adrenal). Emergency radio-chemotherapy was initiated, and the outcome was good, with rapid regression of the iris metastasis and good efficacy against the primary cancer. After one year of follow-up, the patient developed a metastasis at a new site, and his general condition deteriorated.

Keywords: Bronchopulmonary cancer; Cancer bronchopulmonaire; Granulomatous uveitis; Iris metastasis; Métastase irienne; Radio-chemotherapy; Radio-chimiothérapie; Uvéite granulomateuse.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / diagnosis*
  • Adenocarcinoma / drug therapy
  • Adenocarcinoma / pathology*
  • Adenocarcinoma / radiotherapy
  • Adenocarcinoma of Lung
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Cranial Irradiation
  • Humans
  • Iris Neoplasms / diagnosis*
  • Iris Neoplasms / drug therapy
  • Iris Neoplasms / radiotherapy
  • Iris Neoplasms / secondary*
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / drug therapy
  • Lung Neoplasms / pathology*
  • Lung Neoplasms / radiotherapy
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Radiotherapy, Adjuvant