Clival encephalocele and 5q15 deletion: a case report

J Child Neurol. 2015 Mar;30(4):505-8. doi: 10.1177/0883073814530504. Epub 2014 Apr 24.

Abstract

A preterm neonate presenting with respiratory distress after birth was found to have a clival encephalocele, which is a variant of a basal encephalocele, and hypoplasia of the cerebellum. Genetic studies revealed a small deletion of the long arm of chromosome 5: 5q15 deletion. We report a rare variant of a basal encephalocele with a cerebellar malformation and 5q15 deletion.

Keywords: 5q15 deletion; clivus; congenital anomalies; encephalocele; neonate.

Publication types

  • Case Reports

MeSH terms

  • Cerebellum / abnormalities*
  • Cerebellum / diagnostic imaging
  • Chromosomes, Human, Pair 5*
  • Cranial Fossa, Posterior*
  • Encephalocele / diagnostic imaging
  • Encephalocele / pathology*
  • Female
  • Humans
  • Infant, Newborn
  • Magnetic Resonance Imaging
  • Sequence Deletion*
  • Twins
  • Ultrasonography