[Cytokines level in patients with drug-induced jaw necrosis]

Stomatologiia (Mosk). 2014;93(3):28-30.
[Article in Russian]

Abstract

The study included 15 patients with purulent inflammatory diseases of maxillofacial area and 25 patients with facial bone necrosis induced by synthetic drugs. Pro- and anti-inflammatory cytokines levels in saliva and wound fluid were analyzed in two groups. The results proved cytokines to play important role in jaw necrosis induced by drugs containing red phosphorus.

MeSH terms

  • Adult
  • Cytokines / analysis
  • Cytokines / immunology*
  • Female
  • Humans
  • Illicit Drugs / adverse effects*
  • Interleukin-10 / analysis
  • Interleukin-10 / immunology
  • Jaw Diseases / chemically induced*
  • Jaw Diseases / immunology
  • Male
  • Middle Aged
  • Morphine Derivatives / administration & dosage
  • Morphine Derivatives / adverse effects*
  • Osteonecrosis / chemically induced*
  • Osteonecrosis / immunology
  • Saliva / chemistry
  • Saliva / immunology
  • Transforming Growth Factor beta / analysis
  • Transforming Growth Factor beta / immunology
  • Tumor Necrosis Factor-alpha / analysis
  • Tumor Necrosis Factor-alpha / immunology
  • Young Adult

Substances

  • Cytokines
  • Illicit Drugs
  • Morphine Derivatives
  • Transforming Growth Factor beta
  • Tumor Necrosis Factor-alpha
  • Interleukin-10