Small Molecule PAI-1 Functional Inhibitor Attenuates Vascular Smooth Muscle Cell Migration and Survival: Implications for the Therapy of Vascular Disease

New Horiz Transl Med. 2014 Sep 1;2(1):16-19. doi: 10.1016/j.nhtm.2014.08.003.

Authors

Tessa M Simone¹, Paul J Higgins¹

Affiliation

¹ Center for Cell Biology & Cancer Research, Albany Medical College, Albany, New York 12208.

No abstract available

Keywords: PAI-1; SERPIN; Vascular disease; apoptosis; migration; pericellular proteolysis; tiplaxtinin; vascular smooth muscle cells.

Grants and funding

R01 GM057242/GM/NIGMS NIH HHS/United States