Sustained Virologic Response for Chronic Hepatitis C Infection after 27 Days of Treatment with Sofosbuvir and Ribavirin

Eric G Meissner; Amy Nelson; Miriam Marti; Henry Masur; Anu Osinusi; Shyam Kottilil

doi:10.1093/ofid/ofu013

Sustained Virologic Response for Chronic Hepatitis C Infection after 27 Days of Treatment with Sofosbuvir and Ribavirin

Open Forum Infect Dis. 2014 Spring;1(1):013. doi: 10.1093/ofid/ofu013.

Authors

Eric G Meissner¹, Amy Nelson¹, Miriam Marti¹, Henry Masur², Anu Osinusi³, Shyam Kottilil¹

Affiliations

¹ Laboratory of Immunoregulation/NIAID/NIH, Bethesda, MD, 20892 USA.
² Critical Care Medicine Department/Clinical Center/NIH, Bethesda, MD, 20892 USA.
³ Laboratory of Immunoregulation/NIAID/NIH, Bethesda, MD, 20892 USA ; Division of Infectious Diseases, Institute of Human Virology, University of Maryland Medical School, Baltimore, MD, USA.

Abstract

Successful treatment of chronic hepatitis C virus infection can now be achieved using directly acting antiviral agents without interferon. We report a patient who achieved a sustained virologic response after 27 days of treatment with sofosbuvir and ribavirin. Identifying factors that allow for shorter treatment in some individuals is imperative.

Keywords: hepatitis C virus; interferon-free treatment; sofosbuvir; sustained virologic response.

Grants and funding

Z99 CL999999/ImNIH/Intramural NIH HHS/United States