The MRE11 complex: an important source of stress relief

Exp Cell Res. 2014 Nov 15;329(1):162-9. doi: 10.1016/j.yexcr.2014.10.010. Epub 2014 Oct 18.

Authors

Katrin Rein¹, Travis H Stracker²

Affiliations

¹ Institute for Research in Biomedicine (IRB Barcelona), Barcelona, Spain.
² Institute for Research in Biomedicine (IRB Barcelona), Barcelona, Spain. Electronic address: travis.stracker@irbbarcelona.org.

PMID: 25447316
DOI: 10.1016/j.yexcr.2014.10.010

No abstract available

Keywords: Apoptosis; Cancer; Cell cycle checkpoint; DNA damage; DNA repair; Genomic instability; MRE11; NBS1; RAD50; Replication fork.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Ataxia Telangiectasia Mutated Proteins / metabolism*
Carrier Proteins / metabolism*
Cell Transformation, Neoplastic / genetics*
Cell Transformation, Neoplastic / metabolism*
Cell Transformation, Neoplastic / pathology
DNA Replication*
DNA-Binding Proteins / metabolism*
Humans
MRE11 Homologue Protein
Nuclear Proteins / metabolism*

Substances

Carrier Proteins
DNA-Binding Proteins
MRE11 protein, human
Nuclear Proteins
TOPBP1 protein, human
Ataxia Telangiectasia Mutated Proteins
MRE11 Homologue Protein