Monitored viral load: a measure of HIV treatment outcomes in an outpatient setting in Rhode Island

R I Med J (2013). 2014 Jan 5;98(1):26-30.

Abstract

Community viral load measurements have been postulated to be a population-based biomarker of HIV disease. We propose the use of the monitored community viral load (mCVL) as an aggregate measure of viral load among persons receiving HIV care with available HIV-1 plasma viral loads and applied it to our clinic population from 2003-2010. We demonstrated a reduction in mCVL from 16,589 copies/ml to 11,992 copies/ml that correlated with a rising rate of antiretroviral use and HIV viral suppression; however, differences among risk populations were observed. The mCVL is a useful measure of HIV burden among patients in-care; it may reflect the HIV transmission risk in the community and help target preventive interventions.

Keywords: Antiretroviral therapy; Community viral load; HIV; Rhode Island.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Ambulatory Care
  • Anti-HIV Agents / therapeutic use*
  • Cost of Illness
  • Female
  • HIV Infections / drug therapy*
  • HIV Infections / epidemiology
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Rhode Island / epidemiology
  • Risk Factors
  • Treatment Outcome
  • Viral Load / methods
  • Viral Load / statistics & numerical data*
  • Young Adult

Substances

  • Anti-HIV Agents