[Influence of post-traumatic stress disorder on heart rate variability as marker of the autonomic nervous system - a systematic review]

Fortschr Neurol Psychiatr. 2015 Jan;83(1):30-7. doi: 10.1055/s-0034-1398779. Epub 2015 Jan 20.
[Article in German]

Abstract

Introduction: PTSD is associated with comprehensive disruption of several neurobiological regulation mechanisms and with a disruption in the parasympathetic-sympathetic balance. This can be measured with the heart rate variability (HRV).

Methods: A systematic review in PubMed using the keywords "hrv" or "heart rate variability" and "PTSD" or "posttraumatic stress disorder" was performed.

Results: Overall 15 original studies were identified. In most cases a significant relationship of PTSD for reduction of HRV was demonstrated (9 studies) or, respectively, a reduction by trends was shown in 3 studies. Limitations were discussed.

Discussion: In spite of the limitations, most of the studies have shown a relationship between PTSD and HRV. However, an assessment of this potential marker as a supplement for clinical diagnosis and therapy follow-up in patients with PTSD seems to be premature on the basis of the data obtained so far. Further research is required.

Publication types

  • Meta-Analysis
  • Review
  • Systematic Review

MeSH terms

  • Autonomic Nervous System / physiopathology*
  • Biomarkers
  • Heart Rate*
  • Humans
  • Stress Disorders, Post-Traumatic / physiopathology*

Substances

  • Biomarkers