An unusual case of strychnine poisoning

J Forensic Sci. 2015 May;60(3):816-7. doi: 10.1111/1556-4029.12706. Epub 2015 Feb 20.

Abstract

Strychnine-related death has been described since the 19th century. This alkaloid was discovered in 1818. Historically, strychnine was used by the South-East Asian autochthones on their arrows. However, its production was modified by legislation, which was used to protect people against accidental intoxications. Here, we present the case of a 69-year-old man who was found dead at home. During the autopsy, we found a blue substance in the stomach. Toxicological analysis measured strychnine at 0.29 μg/mL in the blood sample, which is a relatively low level in comparison with the results given in the literature. However, histologic examination and toxicological findings permitted the conclusion of strychnine poisoning.

Keywords: Strychnos nux vomica; forensic medicine; forensic pathology; poisoning; rodenticide; strychnine.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Aged
  • Forensic Pathology
  • Forensic Toxicology
  • Gastrointestinal Contents / chemistry
  • Humans
  • Indicators and Reagents / analysis
  • Male
  • Methylene Blue / analysis
  • Poisons*
  • Strychnine / analysis
  • Strychnine / poisoning*
  • Suicide*

Substances

  • Indicators and Reagents
  • Poisons
  • Strychnine
  • Methylene Blue