A cluster of rotavirus enteritis in pediatric liver recipients

Transpl Infect Dis. 2015 Jun;17(3):477-80. doi: 10.1111/tid.12378. Epub 2015 May 19.

Abstract

We observed a cluster of 4 pediatric liver recipients who developed diarrhea in a liver transplant unit within 5 days. Feces from these 4 patients were rotavirus positive when tested with Colloidal Gold Diagnostic Kit. Nucleic acid from 3 fecal specimens was extracted and reverse transcribed. Two were amplified positively. The complementary DNAs were sequenced. Alignment and phylogenetic analysis were performed with MEGA 6.06. Although involving only 4 pediatric liver recipients, this cluster was caused by at least 2 distinct G9P[8] rotavirus strains and included community infection and nosocomial infection.

Keywords: community infection; nosocomial infection; pediatric liver recipients; rotavirus enteritis.

MeSH terms

  • Base Sequence
  • Community-Acquired Infections
  • Cross Infection
  • Diarrhea
  • Feces / virology
  • Female
  • Genotype
  • Humans
  • Infant
  • Liver Transplantation / adverse effects*
  • Male
  • Molecular Sequence Data
  • Phylogeny
  • Rotavirus / genetics
  • Rotavirus / isolation & purification*
  • Rotavirus Infections / epidemiology*
  • Rotavirus Infections / virology
  • Sequence Analysis, DNA

Associated data

  • GENBANK/GU592511
  • GENBANK/HM007177
  • GENBANK/HM007183
  • GENBANK/HM007185
  • GENBANK/JF826511
  • GENBANK/JQ087426
  • GENBANK/KF371733
  • GENBANK/KF371744
  • GENBANK/KF371788
  • GENBANK/KF371865
  • GENBANK/KF371918
  • GENBANK/KF371951
  • GENBANK/KF372006
  • GENBANK/KJ412897
  • GENBANK/KJ794102
  • GENBANK/KJ794103
  • GENBANK/KJ794104
  • GENBANK/KJ794105