A peculiar fibroma-like lesion of superficial soft tissue: morphologic and immunophenotypic evaluation

Pathologica. 2014 Dec;106(4):327-9.

Abstract

Apeculiar lesion of superficial soft tissue characterised by fibroma-like morphology and an immunohistochemical profile consisting of CK+, VIM+, CD34+, CD31+/-, FLI1+ and INI-1 retained is described. The lesion entered into differential diagnosis with the so-called fibroma-like variant of epithelioid sarcoma, with the entities defined as ES-like/pseudomyogenic haemangioendothelioma and the recently identified entity defined as superficial CD34+ fibroblastic tumour. All of these entities share a common morphological structure, but differ in their immunophenotypic profile.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antigens, CD / immunology
  • Diagnosis, Differential
  • Fibroma / diagnosis
  • Fibroma / pathology*
  • Humans
  • Immunohistochemistry
  • Male
  • Sarcoma / diagnosis
  • Sarcoma / pathology*
  • Skin Neoplasms / diagnosis
  • Skin Neoplasms / pathology*

Substances

  • Antigens, CD