Comorbidity Among Dimensions of Childhood Psychopathology: Converging Evidence from Behavior Genetics

Child Dev Perspect. 2015 Mar 1;9(1):26-31. doi: 10.1111/cdep.12102.

Abstract

In this article, we review evidence from recent behavior genetic studies that examined the covariance among common childhood psychopathological conditions and tested specific hypotheses regarding common and broadband-specific underlying features of childhood psychopathology. Specifically, we review the distinction between internalizing and externalizing disorders, the support for the generalist genes and specialist environments model, negative emotionality as a heritable underlying feature common to both internalizing and externalizing disorders, and daring as a heritable broadband-specific underlying feature that distinguishes externalizing disorders from internalizing disorders. We also discuss the implications of research in the search for specific genes that influence childhood psychopathology and suggest avenues for new research.

Keywords: behavior genetics; comorbidity; externalizing; internalizing.