Shape-Controlled Synthesis and Self-Sorting of Covalent Organic Cage Compounds

Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10356-60. doi: 10.1002/anie.201502983. Epub 2015 Jul 1.

Abstract

The directional bonding approach is a powerful tool to rationally control both shape and stoichiometry of three-dimensional objects built from rigid building blocks under dynamic covalent conditions. Co-condensation of catechol-functionalized tribenzotriquinacene derivatives which have 90° angles between the reactive sites and diboronic acids with bite angles of 60°, 120°, and 180°, led to the efficient formation of, respectively, bipyramidal, tetrahedral, or cubic covalent organic cage compounds in a predictable manner. Investigations on the self-sorting of ternary mixtures containing two competitive boronic acids revealed either narcissistic or social self-sorting depending on the stability of the segregated cages relative to feasible three-component assemblies.

Keywords: boronate esters; cages compounds; dynamic covalent chemistry; self-sorting; tribenzotriquinacenes.