Epidemiology of community-onset bloodstream infections in Bouaké, central Côte d'Ivoire

C Akoua-Koffi; H Tia; J K Plo; P Monemo; A Cissé; C Yao; P J Yenan; F S Touré; V Ilupeju; I I Bogoch; J Utzinger; M Herrmann; S L Becker

doi:10.1016/j.nmni.2015.06.009

Epidemiology of community-onset bloodstream infections in Bouaké, central Côte d'Ivoire

New Microbes New Infect. 2015 Jul 16:7:100-4. doi: 10.1016/j.nmni.2015.06.009. eCollection 2015 Sep.

Authors

C Akoua-Koffi¹, H Tia¹, J K Plo², P Monemo¹, A Cissé³, C Yao², P J Yenan², F S Touré¹, V Ilupeju¹, I I Bogoch⁴, J Utzinger⁵, M Herrmann⁶, S L Becker⁷

Affiliations

¹ Laboratoire de Bactériologie-Virologie, Cote d'Ivoire ; Unité de Formation et Recherche Sciences Médicales, Université Alassane Ouattara de Bouaké, Bouaké, Côte d'Ivoire.
² Service de Pédiatrie, Centre Hospitalier Universitaire de Bouaké, Cote d'Ivoire ; Unité de Formation et Recherche Sciences Médicales, Université Alassane Ouattara de Bouaké, Bouaké, Côte d'Ivoire.
³ Laboratoire de Bactériologie-Virologie, Cote d'Ivoire.
⁴ Department of Medicine, University of Toronto, Toronto, Ontario, Canada ; Divisions of Internal Medicine and Infectious Diseases, Toronto General Hospital, Toronto, Ontario, Canada.
⁵ Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Switzerland ; University of Basel, Basel, Switzerland.
⁶ Institute of Medical Microbiology and Hygiene, Saarland University, Homburg/Saar, Germany.
⁷ Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Switzerland ; University of Basel, Basel, Switzerland ; Institute of Medical Microbiology and Hygiene, Saarland University, Homburg/Saar, Germany.

Abstract

Bacterial bloodstream infections (BSI) account for considerable morbidity worldwide, but epidemiological data from resource-constrained tropical settings are scarce. We analysed 293 blood cultures from patients presenting to a regional referral hospital in Bouaké, central Côte d'Ivoire, to determine the aetiology of community-onset BSI. The prevalence of bacteraemia was 22.5%, with children being most commonly affected. Enterobacteriaceae (predominantly Klebsiella pneumoniae and Salmonella enterica) accounted for 94% of BSI. Staphylococcus aureus was the only relevant Gram-positive pathogen. Clinical signs and symptoms were not significantly associated with blood culture positivity after controlling for malaria.

Keywords: Bacteraemia; Côte d’Ivoire; Enterobacteriaceae; Klebsiella pneumoniae; Salmonella enterica.