Weak uptake of 123I-MIBG and 18F-FDOPA contrasting with high 18F-FDG uptake in stage I neuroblastoma

Clin Nucl Med. 2015 Dec;40(12):969-70. doi: 10.1097/RLU.0000000000000957.

Abstract

Hypertension in a 6-year-old girl was the presenting sign of a stage I neuroblastoma. This tumor corresponded to a left adrenal gland mass. Hypertension resolved immediately after complete surgical resection of the tumor with an uneventful follow-up (24 months at the present time). Preoperative assessment by nuclear medicine techniques showed weak uptake of I-MIBG and F-FDOPA contrasting with high F-FDG uptake by the tumor.

Publication types

  • Case Reports

MeSH terms

  • 3-Iodobenzylguanidine*
  • Brain Neoplasms / diagnostic imaging*
  • Brain Neoplasms / pathology
  • Child
  • Dihydroxyphenylalanine / analogs & derivatives*
  • Female
  • Fluorodeoxyglucose F18*
  • Humans
  • Neuroblastoma / diagnostic imaging*
  • Neuroblastoma / pathology
  • Positron-Emission Tomography
  • Radiopharmaceuticals*

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18
  • fluorodopa F 18
  • 3-Iodobenzylguanidine
  • Dihydroxyphenylalanine