Epidural diamorphine and bupivacaine in labour

Anaesthesia. 1989 May;44(5):400-3. doi: 10.1111/j.1365-2044.1989.tb11338.x.

Abstract

A double-blind randomised study was performed to assess the analgesic effect of epidural diamorphine, administered with bupivacaine, on primigravid women in labour. Fifty patients received 0.25% bupivacaine 10 ml via the epidural catheter as their initial dose; patients in Group 1 received diamorphine 5 mg with the bupivacaine. A 0.1% bupivacaine infusion was started at 10 minutes and bolus doses of bupivacaine were given if required. There was a significant reduction in rate of bupivacaine administration, pain scores at 20 and 30 minutes, number of supplements required, and degree of motor blockade in the diamorphine group.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Analgesia, Epidural*
  • Anesthesia, Obstetrical*
  • Bupivacaine* / administration & dosage
  • Bupivacaine* / adverse effects
  • Clinical Trials as Topic
  • Double-Blind Method
  • Female
  • Heroin* / administration & dosage
  • Heroin* / adverse effects
  • Humans
  • Labor, Obstetric*
  • Pregnancy
  • Random Allocation

Substances

  • Heroin
  • Bupivacaine