Recent applications of ring-rearrangement metathesis in organic synthesis

Beilstein J Org Chem. 2015 Oct 7:11:1833-64. doi: 10.3762/bjoc.11.199. eCollection 2015.

Abstract

Ring-rearrangement metathesis (RRM) involves multiple metathesis processes such as ring-opening metathesis (ROM)/ring-closing metathesis (RCM) in a one-pot operation to generate complex targets. RRM delivers complex frameworks that are difficult to assemble by conventional methods. The noteworthy point about this type of protocol is multi-bond formation and it is an atom economic process. In this review, we have covered literature that appeared during the last seven years (2008-2014).

Keywords: Diels–Alder chemistry; green chemistry; natural products; olefin metathesis; polycycles; ring-rearrangement metathesis.

Publication types

  • Review