Additional Protein Fortification Is Necessary in Extremely Low-Birth-Weight Infants Fed Human Milk

J Pediatr Gastroenterol Nutr. 2016 Jul;63(1):103-5. doi: 10.1097/MPG.0000000000001142.

Abstract

In the present study, approximately one in three (49/152, 32.2%) extremely low-birth-weight infants were demonstrated to require additional protein intake to supplement the standard fortification to achieve satisfactory weight gain. This additional protein fortification also resulted in a rapid increase in length-for-age (P < 0.001) and head circumference-for-age (P = 0.02) z scores.

Trial registration: ClinicalTrials.gov NCT02515266.

MeSH terms

  • Dietary Proteins / administration & dosage*
  • Female
  • Food, Fortified*
  • Gestational Age
  • Humans
  • Infant Food / analysis*
  • Infant Nutritional Physiological Phenomena
  • Infant, Low Birth Weight / growth & development*
  • Infant, Newborn
  • Male
  • Milk, Human / chemistry*
  • Nutritional Requirements
  • Weight Gain

Substances

  • Dietary Proteins

Associated data

  • ClinicalTrials.gov/NCT02515266