Thrombophilic status may predict prognosis in patients with metastatic BRAFV600-mutated melanoma who are receiving BRAF inhibitors

J Am Acad Dermatol. 2016 Jun;74(6):1254-1256.e4. doi: 10.1016/j.jaad.2015.11.006.
No abstract available

Publication types

  • Letter

MeSH terms

  • Algorithms
  • Biomarkers / blood
  • Blood Coagulation
  • Disease-Free Survival
  • Female
  • Fibrin Fibrinogen Degradation Products / metabolism*
  • Humans
  • Male
  • Melanoma / blood
  • Melanoma / drug therapy*
  • Melanoma / genetics
  • Melanoma / secondary*
  • Mutation
  • Neoplasm Staging
  • Prognosis
  • Protein Kinase Inhibitors / therapeutic use
  • Proto-Oncogene Proteins B-raf / genetics
  • Skin Neoplasms / blood
  • Skin Neoplasms / drug therapy*
  • Skin Neoplasms / genetics
  • Skin Neoplasms / pathology*
  • Survival Rate
  • Thrombophilia / blood*

Substances

  • Biomarkers
  • Fibrin Fibrinogen Degradation Products
  • Protein Kinase Inhibitors
  • fibrin fragment D
  • BRAF protein, human
  • Proto-Oncogene Proteins B-raf