Neuroimaging in Central Nervous System Lymphoma

Seyed Ali Nabavizadeh; Arastoo Vossough; Mehrdad Hajmomenian; Reza Assadsangabi; Suyash Mohan

doi:10.1016/j.hoc.2016.03.005

Neuroimaging in Central Nervous System Lymphoma

Hematol Oncol Clin North Am. 2016 Aug;30(4):799-821. doi: 10.1016/j.hoc.2016.03.005.

Authors

Seyed Ali Nabavizadeh¹, Arastoo Vossough², Mehrdad Hajmomenian², Reza Assadsangabi², Suyash Mohan³

Affiliations

¹ Department of Radiology, Division of Neuroradiology, Perelman School of Medicine at University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19014, USA.
² Department of Radiology, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.
³ Department of Radiology, Division of Neuroradiology, Perelman School of Medicine at University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19014, USA. Electronic address: Suyash.Mohan@uphs.upenn.edu.

PMID: 27443998
DOI: 10.1016/j.hoc.2016.03.005

Abstract

Primary central nervous system lymphoma (PCNSL) is a rare aggressive high-grade type of extranodal lymphoma. PCNSL can have a variable imaging appearance and can mimic other brain disorders such as encephalitis, demyelination, and stroke. In addition to PCNSL, the CNS can be secondarily involved by systemic lymphoma. Computed tomography and conventional MRI are the initial imaging modalities to evaluate these lesions. Recently, however, advanced MRI techniques are more often used in an effort to narrow the differential diagnosis and potentially inform diagnostic and therapeutic decisions.

Keywords: CT; Central nervous system; Lymphoma; MRI.

Publication types

Review

MeSH terms

Central Nervous System Neoplasms / diagnostic imaging*
Central Nervous System Neoplasms / therapy
Humans
Lymphoma / diagnostic imaging*
Lymphoma / therapy
Neuroimaging / methods*