Solvent-Controlled, Tunable Hydrosulfonylation of 3-Cyclopropylideneprop-2-en-1-ones

Org Lett. 2016 Sep 2;18(17):4292-5. doi: 10.1021/acs.orglett.6b02047. Epub 2016 Aug 16.

Abstract

An interesting and tunable hydrosulfonylation of 3-cyclopropylideneprop-2-en-1-ones with sodium sulfinates and acetic acid is described. The corresponding β- or γ-addition products can be produced in good to excellent yields with high selectivities, respectively. A rationale for these transformations is proposed base on the controlled experiments.

Publication types

  • Research Support, Non-U.S. Gov't