A path toward understanding neurodegeneration

K S Kosik; T J Sejnowski; M E Raichle; A Ciechanover; D Baltimore

doi:10.1126/science.aai7622

A path toward understanding neurodegeneration

Science. 2016 Aug 26;353(6302):872-3. doi: 10.1126/science.aai7622.

Authors

K S Kosik¹, T J Sejnowski², M E Raichle³, A Ciechanover⁴, D Baltimore⁵

Affiliations

¹ Department of Molecular, Cellular, and Developmental Biology, Neuroscience Research Institute, University of California, Santa Barbara, Santa Barbara, CA 93106, USA. kosik@lifesci.ucsb.edu baltimo@caltech.edu.
² Howard Hughes Medical Institute at the Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.
³ Mallinckrodt Institute of Radiology, Department of Neurology, Department of Biomedical Engineering, Department of Anatomy and Neurobiology, Washington University in St. Louis, St. Louis, MO 63110, USA.
⁴ Cancer and Vascular Biology Research Center, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 31096, Israel.
⁵ Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. kosik@lifesci.ucsb.edu baltimo@caltech.edu.

Abstract

Understanding the fundamental basis of neurodegeneration requires a focus on cell biology (colored scanning electron micrograph of a neuron is shown).

MeSH terms

Cell Biology / trends
Disease Progression
Humans
Neurodegenerative Diseases* / pathology
Neurodegenerative Diseases* / prevention & control
Neurodegenerative Diseases* / therapy

Grants and funding

R01 EB009282/EB/NIBIB NIH HHS/United States