Granular parakeratosis induced by benzalkonium chloride exposure from laundry rinse aids

Australas J Dermatol. 2017 Aug;58(3):e138-e140. doi: 10.1111/ajd.12551. Epub 2016 Sep 19.

Abstract

Benzalkonium chloride is a quaternary ammonium cationic detergent present in a number of household products, which can act as a major skin irritant. We present the case of six children who developed granular parakeratosis after exposure to benzalkonium chloride in laundry rinse aids, presenting as a brightly erythematous, tender but minimally pruritic, intertriginous eruption followed by superficial desquamation. The eruptions resolved over 3-4 weeks after cessation of exposure.

Keywords: benzalkonium chloride; contact dermatitis; granular parakeratosis.

MeSH terms

  • Adolescent
  • Benzalkonium Compounds / adverse effects*
  • Child
  • Child, Preschool
  • Female
  • Household Products / adverse effects*
  • Humans
  • Laundering
  • Male
  • Parakeratosis / chemically induced*
  • Parakeratosis / pathology*

Substances

  • Benzalkonium Compounds