Mitochondrial Amino Acid Metabolism Provides Vulnerabilities in Mutant KRAS-Driven Cancers

Gastroenterology. 2016 Nov;151(5):798-801. doi: 10.1053/j.gastro.2016.09.036. Epub 2016 Oct 3.

Authors

Yatrik M Shah¹, Costas A Lyssiotis²

Affiliations

¹ Department of Molecular and Integrative Physiology and Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan. Electronic address: shahy@umich.edu.
² Department of Molecular and Integrative Physiology and Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan. Electronic address: clyssiot@med.umich.edu.

PMID: 27713037
DOI: 10.1053/j.gastro.2016.09.036

No abstract available

Publication types

Editorial
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Amino Acids
Cell Line, Tumor
Lung Neoplasms
Mitochondria*
Mutation
Neoplasms
Proto-Oncogene Proteins p21(ras) / genetics*

Substances

Amino Acids
Proto-Oncogene Proteins p21(ras)