Anaphylaxis Conundrum: A Trojan Horse Phenomenon

J Allergy Clin Immunol Pract. 2017 Mar-Apr;5(2):325-329. doi: 10.1016/j.jaip.2016.08.008. Epub 2016 Oct 17.

Abstract

Anaphylaxis is a serious and potentially life-threatening allergic reaction that may follow the ingestion of foods. Although these reactions usually follow a common clinical pattern and often demonstrate IgE sensitization to the antigen in question, both the clinical presentation and causative allergen may be atypical, surprising, and difficult to identify. Failure to identify the actual cause of the reaction can compromise treatment and complicate long-term care. Here, we present a patient who had symptoms of anaphylaxis after eating salmon, but confirmation of the causative allergen was not readily apparent. This particular case serves as an insightful lesson for patients undergoing evaluation for anaphylaxis and also provides a framework for navigating through a case involving identification of an underlying allergen.

Keywords: Anaphylaxis; Anisakis allergy.

Publication types

  • Case Reports
  • Clinical Conference
  • Review

MeSH terms

  • Allergens / immunology*
  • Anaphylaxis / diagnosis*
  • Anaphylaxis / etiology
  • Animals
  • Anisakis / immunology*
  • Antigens, Helminth / immunology*
  • Female
  • Fish Proteins / immunology*
  • Food Hypersensitivity / complications
  • Food Hypersensitivity / diagnosis*
  • Food Hypersensitivity / diet therapy
  • Humans
  • Immunoglobulin E / blood
  • Middle Aged
  • Salmon / immunology*
  • Salmon / parasitology

Substances

  • Allergens
  • Antigens, Helminth
  • Fish Proteins
  • Immunoglobulin E