Abstract
A long-standing goal of cardiovascular scientists is to repair damaged hearts following myocardial infarction by overcoming the limited regenerative capacity of the adult mammalian heart. A number of new strategies are being actively investigated for generating functional cardiomyocytes or progenitor cells. The race is on for the first demonstration of durable therapeutic heart repair in human.
Keywords:
cell cycle; myocardial infarction; regenerative medicine; stem cell cardiac patch.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult Stem Cells / cytology
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Aging / physiology
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Animals
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Animals, Newborn
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Cell Plasticity
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Cell Transplantation / methods
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Cellular Reprogramming Techniques
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Fibroblasts / cytology
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Heart / growth & development
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Heart / physiology*
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Heart Failure / pathology
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Heart Failure / physiopathology
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Heart Failure / therapy*
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Humans
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Mammals
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Myocytes, Cardiac / cytology
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Myocytes, Cardiac / physiology
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Pluripotent Stem Cells / cytology
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Regeneration / physiology*