Chromosomal mapping of the prolactin/growth hormone gene family in the mouse

Endocrinology. 1988 Jun;122(6):2462-6. doi: 10.1210/endo-122-6-2462.

Abstract

The chromosomal assignments of genes in the PRL/GH family in the mouse have been determine in mouse-hamster hybrid cell lines. Mouse GH (mGH) appears to be encoded by a single copy gene located on chromosome 11 and is part of a highly conserved region between mouse chromosome 11 and human chromosome 17. All of the other genes in this hormone family, including those encoding mPRL, mouse placental lactogens I and II, and mouse proliferin and proliferin-related protein, map to chromosome 13.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Chromosome Mapping*
  • Cricetinae
  • DNA / genetics
  • DNA Restriction Enzymes
  • DNA, Recombinant
  • Deoxyribonuclease EcoRI
  • Glycoproteins / genetics
  • Growth Hormone / genetics*
  • Hybrid Cells
  • Intercellular Signaling Peptides and Proteins
  • Mice
  • Nucleic Acid Hybridization
  • Placental Lactogen / genetics
  • Pregnancy Proteins / genetics
  • Prolactin / genetics*

Substances

  • DNA, Recombinant
  • Glycoproteins
  • Intercellular Signaling Peptides and Proteins
  • Pregnancy Proteins
  • Prl2c2 protein, mouse
  • Prolactin
  • Growth Hormone
  • DNA
  • Placental Lactogen
  • DNA Restriction Enzymes
  • Deoxyribonuclease EcoRI