Surgical Treatment of a Double Origin Posterior Inferior Cerebellar Artery Aneurysm and Insights From Embryology: Case Report and Literature Review

Oper Neurosurg (Hagerstown). 2017 Jun 1;13(3):E8-E12. doi: 10.1093/ons/opx002.

Abstract

Background and importance: Aneurysms affecting double origin (DO) posterior inferior cerebellar artery (PICA) variants are rare. Most reports describe endovascular occlusion of the affected branch to treat the aneurysm, but we describe a patient in which open surgical sacrifice of 1 branch resulted in insufficient perfusion.

Clinical presentation: We report the only case of open surgical treatment of an aneurysm affecting a leg of a DOPICA. A 42-year-old woman presenting with the worst headache of her life was found to have a DOPICA aneurysm and initially treated by trapping the aneurysm. Intraoperative indocyanine green imaging revealed insufficient perfusion through the caudal branch, which was remediated by end-to-end anastomosis to preserve flow through both origins. The patient made a full recovery.

Conclusion: Treating a DOPICA aneurysm by sacrificing 1 of the origins is not possible for all patients. This first report of open surgical treatment of a DOPICA leg aneurysm suggests that 1 or both branches may be required for sufficient perfusion, and the unique embryology of DOPICA development suggests a possible mechanism.

Keywords: Cerebrovascular embryology; Double origin posterior inferior cerebellar artery; Intracranial vasculogenesis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Cerebral Angiography
  • Embolization, Therapeutic / methods*
  • Female
  • Humans
  • Intracranial Aneurysm / diagnostic imaging
  • Intracranial Aneurysm / surgery*
  • Neurosurgical Procedures / methods*
  • Vertebral Artery / diagnostic imaging
  • Vertebral Artery / surgery*