Congenital Herpes Simplex Virus Type 1 Infection Mimicking Congenital Erosive and Vesicular Dermatosis: Possible Pathogenic Insights

Andrew W Swarbrick; Christopher C Blyth; Anne R Halbert

doi:10.1111/pde.13166

Congenital Herpes Simplex Virus Type 1 Infection Mimicking Congenital Erosive and Vesicular Dermatosis: Possible Pathogenic Insights

Pediatr Dermatol. 2017 Jul;34(4):e168-e170. doi: 10.1111/pde.13166. Epub 2017 May 25.

Authors

Andrew W Swarbrick¹, Christopher C Blyth^{2

3}, Anne R Halbert¹

Affiliations

¹ Department of Pediatric Dermatology, Princess Margaret Hospital for Children, Subiaco, Western Australia, Australia.
² School of Pediatrics and Child Health, University of Western Australia, Perth, Western Australia, Australia.
³ Department of Infectious Diseases, Princess Margaret Hospital for Children, Subiaco, Western Australia, Australia.

PMID: 28543846
DOI: 10.1111/pde.13166

Abstract

Congenital erosive and vesicular dermatosis (CEVD) is a rare entity of unknown etiology. We report a case of congenital herpes simplex virus (HSV) type 1 infection that healed with reticulated and supple scarring, similar to that seen in CEVD. Twenty percent of previously reported cases of CEVD had recurrent HSV infection throughout the first year of life. We postulate that at least some previous cases of CEVD may have been due to undiagnosed congenital HSV infection.

Publication types

Case Reports

MeSH terms

Acyclovir / therapeutic use*
Antiviral Agents / therapeutic use*
Diagnosis, Differential
Female
Herpes Simplex / diagnosis*
Herpes Simplex / drug therapy
Herpesvirus 1, Human / genetics*
Humans
Infant, Newborn
Skin Diseases, Vesiculobullous / diagnosis*

Substances

Antiviral Agents
Acyclovir