Predictive autoimmunity using autoantibodies: screening for anti-nuclear antibodies

Dolores Pérez; Boris Gilburd; Óscar Cabrera-Marante; Jose A Martínez-Flores; Manuel Serrano; Laura Naranjo; Daniel Pleguezuelo; Luis Morillas; Ora Shovman; Estela Paz-Artal; Yehuda Shoenfeld; Antonio Serrano

doi:10.1515/cclm-2017-0241

Predictive autoimmunity using autoantibodies: screening for anti-nuclear antibodies

Clin Chem Lab Med. 2018 Sep 25;56(10):1771-1777. doi: 10.1515/cclm-2017-0241.

Affiliations

¹ Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel.
² Department of Immunology, Instituto de Investigación, Madrid, Spain.
³ Department of Rheumatology, Hospital Universitario, Madrid, Spain.
⁴ MaACR, Head of Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel Hashomer 52621, Israel, Phone: (972) 52-6669020, Fax: (972-3) 5352855; Sackler Faculty of Medicine, Tel-Aviv University, Israel; Incumbent of the Laura Schwarz-Kipp Chair for Research of Autoimmune Diseases, Sackler Faculty of Medicine, Tel-Aviv University, Israel.

PMID: 28628475
DOI: 10.1515/cclm-2017-0241

No abstract available

Keywords: BioPlex ANA Screen; high sensitivity; indirect immunofluorescence; positive predictive value; predictive autoantibodies; systemic autoimmune rheumatic diseases.

MeSH terms

Adult
Aged
Antibodies, Antinuclear / analysis*
Autoimmune Diseases / diagnosis*
Automation
Cell Line
Female
Fluorescent Antibody Technique, Indirect / methods*
Follow-Up Studies
Humans
Male
Middle Aged
Predictive Value of Tests
Reagent Kits, Diagnostic

Substances

Antibodies, Antinuclear
Reagent Kits, Diagnostic