An Indian Family with Tyrosine Hydroxylase Deficiency

Indian Pediatr. 2017 Jun 15;54(6):499-501. doi: 10.1007/s13312-017-1055-9.

Abstract

Background: Tyrosine Hydroxylase deficiency is a rare neurotransmitter disorder.

Case characteristics: An Indian family with the disorder.

Observations: Phenotypic variation, elevated serum prolactin, genetic confirmation, and partial treatment-responsiveness.

Message: Tyrosine Hydroxylase deficiency is a treatable inborn error of metabolism and serum prolactin assists in diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Dopamine Agents / therapeutic use
  • Dystonic Disorders / congenital*
  • Female
  • Humans
  • India
  • Infant
  • Levodopa / therapeutic use
  • Male
  • Tyrosine 3-Monooxygenase / genetics

Substances

  • Dopamine Agents
  • Levodopa
  • Tyrosine 3-Monooxygenase

Supplementary concepts

  • Segawa syndrome, autosomal recessive