Diagnostic criteria, severity classification and guidelines of lichen sclerosus et atrophicus

J Dermatol. 2018 Aug;45(8):891-897. doi: 10.1111/1346-8138.14171. Epub 2017 Dec 19.

Abstract

We established diagnostic criteria and severity classification of lichen sclerosus et atrophicus, because there is no established diagnostic criteria or widely accepted severity classification of the disease. Also, there is no clinical guideline for lichen sclerosus et atrophicus in Japan, so we proposed its clinical guideline. The clinical guidelines were formulated by clinical questions and recommendations on the basis of evidence-based medicine according to the New Minds Clinical Practice Guideline Creation Manual (version 1.0). We aimed to make the guidelines easy to use and reliable including the newest evidence, and to present guidance for various clinical problems in treatment of lichen sclerosus et atrophicus.

Keywords: diagnostic criteria; guideline; lichen sclerosus; severity classification; treatment.

Publication types

  • Practice Guideline

MeSH terms

  • Administration, Cutaneous
  • Age Factors
  • Biopsy
  • Diagnosis, Differential
  • Female
  • Glucocorticoids / therapeutic use*
  • Humans
  • Lichen Sclerosus et Atrophicus / diagnosis*
  • Lichen Sclerosus et Atrophicus / pathology
  • Lichen Sclerosus et Atrophicus / therapy
  • Male
  • Ointments
  • Phototherapy / methods
  • Severity of Illness Index*
  • Sex Factors
  • Skin / pathology*
  • Tacrolimus / therapeutic use
  • Treatment Outcome

Substances

  • Glucocorticoids
  • Ointments
  • Tacrolimus