Timing of Operative Intervention in Traumatic Spine Injuries Without Neurological Deficit

Neurosurgery. 2018 Nov 1;83(5):1015-1022. doi: 10.1093/neuros/nyx569.

Abstract

Background: Numerous studies have demonstrated the benefits of early decompression and stabilization in unstable spine injuries with incomplete neurological deficits. However, a clear consensus on timing to operative intervention still does not exist in those with a normal neurological exam and unstable spine.

Objective: To determine the optimal timing of operative intervention in traumatic spine injuries without neurological deficit.

Methods: Retrospective chart review at a single institution was performed including patients with traumatic spine injuries without neurological deficit admitted from December 2001 to August 2012. Estimated intraoperative blood loss (EBL), in-hospital complications, postoperative hospital length of stay (HLOS), intensive care unit length of stay (ICULOS), and ventilator days were recorded. Delayed surgery was defined as surgery 72 h after admission.

Results: A total of 456 patients were included for analysis. There was a trend towards statistical significance between the time to operative intervention and EBL in bivariate analysis (P = .07). In the risk-adjusted multivariable analysis delayed vs early surgery was not associated with increased EBL or complications. Delayed surgery was associated with increased ICULOS (odds ratio [OR] = 2.19; 95% confidence interval [CI]: 1.38-3.51; P = .001), ventilator days (OR = 2.09; 95% CI: 1.28-3.43; P = .004), and increased postoperative HLOS (OR = 1.84; 95% CI: 1.22-2.76; P = .004).

Conclusion: Earlier operative intervention was associated with decreased ICULOS, ventilator days, and postoperative HLOS and did not show a statistically significant increase in EBL or complications. Earlier operative intervention for traumatic spine injuries without neurological deficit provides better outcomes compared to delayed surgery.

MeSH terms

  • Adult
  • Blood Loss, Surgical / statistics & numerical data
  • Decompression, Surgical / methods
  • Female
  • Humans
  • Length of Stay / statistics & numerical data
  • Middle Aged
  • Neurosurgical Procedures / adverse effects
  • Neurosurgical Procedures / methods*
  • Postoperative Complications / epidemiology
  • Retrospective Studies
  • Spinal Fractures / surgery*
  • Time-to-Treatment*