Optimization of the CT component of SPECT-CT and establishment of local CT diagnostic reference levels for clinical practice

Nucl Med Commun. 2018 Jun;39(6):493-499. doi: 10.1097/MNM.0000000000000831.

Abstract

Objective: The aim of this study was to perform a process of optimization and establish local diagnostic reference levels (DRLs) for the computed tomography (CT) component of single-photon emission computed tomography (SPECT)-CT imaging, for use in clinical practice.

Methods: A multidisciplinary group defined categories for the clinical purpose of the CT component of local SPECT-CT examinations. Each of the examinations were assigned a category, and optimization of acquisition and reconstruction parameters was performed to achieve the required image quality. Dose data were collated for 754 SPECT-CT scans performed on three systems over 10 months. The third quartile values for volume CT dose index and dose length product were calculated and established as local DRLs.

Results: Four categories of CT examinations were defined: attenuation correction; localization and attenuation correction; localization, characterization and attenuation correction; and diagnostic and attenuation correction. Local DRLs were established for 11 examinations. Reference was made to the proposed national DRLs set by a recent UK survey.

Conclusion: This work describes a process of optimization and the creation of practical and effective local DRLs. These can be used in local audit of practice. In future, improved descriptors and standardization of SPECT-CT use would allow more practicable UK national DRLs to be created.

MeSH terms

  • Humans
  • Image Processing, Computer-Assisted*
  • Radiation Dosage
  • Reference Values
  • Single Photon Emission Computed Tomography Computed Tomography / standards*