Drug-induced peripheral neuropathy in a patient with psoriatic arthritis

Arthritis Rheum. 1987 Feb;30(2):221-4. doi: 10.1002/art.1780300214.

Abstract

A patient with psoriatic arthritis developed a peripheral neuropathy while taking hydroxychloroquine and naproxen. Although it was initially suspected that hydroxychloroquine was responsible for the neuropathy, subsequent rechallenge with naproxen demonstrated that clinical and electrophysiologic findings were related to routine pharmacologic doses of naproxen.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Arthritis / drug therapy*
  • Drug Therapy, Combination
  • Female
  • Humans
  • Hydroxychloroquine / administration & dosage
  • Naproxen / administration & dosage
  • Naproxen / adverse effects*
  • Neural Conduction
  • Peripheral Nervous System Diseases / chemically induced*
  • Peripheral Nervous System Diseases / physiopathology
  • Psoriasis / drug therapy*

Substances

  • Hydroxychloroquine
  • Naproxen