Plasma DNA for early cancer detection - opportunities and challenges

Expert Rev Mol Diagn. 2019 Jan;19(1):5-7. doi: 10.1080/14737159.2019.1555476. Epub 2018 Dec 10.

Authors

Wai Kei Jacky Lam^{1

2

3}, Kwan Chee Allen Chan^{1

2

3}

Affiliations

¹ a Department of Chemical Pathology , The Chinese University of Hong Kong, Prince of Wales Hospital , Hong Kong SAR, China.
² b Li Ka Shing Institute of Health Sciences , The Chinese University of Hong Kong , Hong Kong SAR, China.
³ c State Key Laboratory of Translational Oncology , The Chinese University of Hong Kong , Hong Kong SAR, China.

PMID: 30513010
DOI: 10.1080/14737159.2019.1555476

No abstract available

Keywords: Liquid Biopsy; cancer screening; copy number aberrations; epigenome; plasma DNA tissue mapping.

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Biomarkers, Tumor / blood*
Biomarkers, Tumor / genetics
Cell-Free Nucleic Acids / blood*
Cell-Free Nucleic Acids / genetics
Early Detection of Cancer / methods
Humans
Mutation
Neoplasms / blood
Neoplasms / diagnosis*
Neoplasms / genetics
Sequence Analysis, DNA / methods

Substances

Biomarkers, Tumor
Cell-Free Nucleic Acids