Progress in diagnosing and managing cardiac amyloidosis

Mazen Hanna; Chetan Huded; E Rene Rodriguez; Dermot Phelan; Deborah Kwon; Wael Jaber; Jason Valent; Michael Zhen-Yu Tong

doi:10.3949/ccjm.86gr.18004

Progress in diagnosing and managing cardiac amyloidosis

Cleve Clin J Med. 2019 Jan;86(1):29-37. doi: 10.3949/ccjm.86gr.18004.

Authors

Mazen Hanna¹, Chetan Huded², E Rene Rodriguez^{3

4}, Dermot Phelan⁵, Deborah Kwon^{6

7}, Wael Jaber⁸, Jason Valent⁹, Michael Zhen-Yu Tong¹⁰

Affiliations

¹ Co-Director, Amyloidosis Center, Section of Heart Failure and Cardiac Transplant Medicine, Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA. hammam@ccf.org.
² Resident Fellow, Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA.
³ Director, Cardiovascular Pathology, Director, Autopsy Pathology, Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH, USA.
⁴ Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
⁵ Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA.
⁶ Director of Cardiac MRI Research, Department of Cardiovascular Medicine and Department of Diagnostic Radiology, Cleveland Clinic, Cleveland, OH, USA.
⁷ Assistant Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
⁸ Department of Cardiovascular Medicine, Heart and Vascular Institute, and Department of Nuclear Medicine, Cleveland Clinic, Cleveland, OH, USA.
⁹ Department of Hematology and Medical Oncology, Cleveland Clinic, Cleveland, OH, USA.
¹⁰ Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, OH, USA.

PMID: 30624188
DOI: 10.3949/ccjm.86gr.18004

Abstract

The last decade has seen major advances in diagnosing and treating cardiac amyloidosis. Early diagnosis can often now be made using noninvasive laboratory testing and imaging. New treatments are effective and well tolerated.

Publication types

Review

MeSH terms

Amyloidosis / diagnosis*
Amyloidosis / therapy*
Cardiomyopathies / diagnosis*
Cardiomyopathies / therapy*
Humans