An unusual case of aggregatibacter aphrophilus liver abscess

Pan Afr Med J. 2018 Oct 17:31:115. doi: 10.11604/pamj.2018.31.115.16409. eCollection 2018.

Abstract

Liver abscess of oropharyngeal origin in an immunocompetent patient is a rare condition. Furthermore, microbiologic diagnosis of liver abscess can be challenging due to the tremendous diversity of the microorganisms implicated and culture difficulties under laboratory conditions. We report a case of a previously healthy 23-year-old male, who presented multiple liver abscesses, attributed to aggregatibacter aphrophilus, an obligatory oral gram-negative microorganism, that normally is a component of the commensal oral microbiota and non-virulent. The etiopathogenic microorganism was identified after needle aspiration of a liver abscess cavity. Treatment with broad-spectrum antimicrobials and percutaneous catheter drainage under computed tomography guidance of both abscesses, resulted in full recovery. A. aphrophilus represents a rare entity of liver abscess in healthy individuals and suggests that a pathogen of oropharyngeal origin should be suspected when an overt source of infection cannot be documented.

Keywords: Liver; abscess; aggregatibacter aphrophilus; immunocompetent; oropharyngeal.

Publication types

  • Case Reports

MeSH terms

  • Aggregatibacter aphrophilus / isolation & purification*
  • Anti-Bacterial Agents / administration & dosage
  • Drainage / methods
  • Humans
  • Liver Abscess / diagnosis*
  • Liver Abscess / microbiology
  • Liver Abscess / therapy
  • Male
  • Pasteurellaceae Infections / diagnosis*
  • Pasteurellaceae Infections / therapy
  • Tomography, X-Ray Computed
  • Young Adult

Substances

  • Anti-Bacterial Agents