Treatment specific toxicities: Hormones, antihormones, radiation therapy

Semin Oncol. 2019 Dec;46(6):414-420. doi: 10.1053/j.seminoncol.2019.01.006. Epub 2019 Nov 19.

Abstract

Session IV of the Second International Colloquium on Cardio-Oncology held in Kraków, focused on the cardiovascular risks of using hormone replacement therapy in breast cancer and androgen deprivation therapy in prostate cancer and continued the theme from Session 3 with a discussion of risk reduction strategies. The discussion then moved to an overview of modern radiation therapy and evolving mechanisms of cardioprotection. The risks and late cardiotoxic effects that must be considered in patients treated prior to the "modern era" were enumerated stressing the importance of long term follow-up of this population.

Keywords: Antihormones; Cardiovascular events; Hormones; Prevention; Radiation therapy.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents, Hormonal / adverse effects*
  • Antineoplastic Agents, Hormonal / therapeutic use
  • Cardiovascular Diseases / diagnosis
  • Cardiovascular Diseases / etiology
  • Cardiovascular Diseases / prevention & control
  • Cardiovascular Diseases / therapy
  • Combined Modality Therapy / adverse effects
  • Combined Modality Therapy / methods
  • Humans
  • Neoplasms / complications*
  • Neoplasms / mortality
  • Neoplasms / therapy*
  • Radiotherapy / adverse effects*
  • Radiotherapy / methods
  • Risk Factors

Substances

  • Antineoplastic Agents, Hormonal