Recurrent Pneumococcal Meningitis Secondary to Nasoethmoidal Meningocele

Pediatr Infect Dis J. 2020 Feb;39(2):e17-e19. doi: 10.1097/INF.0000000000002520.

Abstract

Since the widespread introduction of the conjugate pneumococcal vaccine and subsequent decline of invasive pneumococcal disease in children, a significant proportion of children with pneumococcal meningitis are identified as having an underlying immunodeficiency or predisposing anatomic abnormality. We present 3 cases of recurrent pneumococcal meningitis where detailed neuro-imaging revealed subtle anterior base of skull defects not detected on initial investigations.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use
  • Biomarkers
  • Child, Preschool
  • Female
  • Humans
  • Leukocyte Count
  • Magnetic Resonance Imaging
  • Male
  • Meningitis, Pneumococcal / diagnosis*
  • Meningitis, Pneumococcal / drug therapy
  • Meningitis, Pneumococcal / etiology*
  • Meningitis, Pneumococcal / prevention & control
  • Meningocele / complications*
  • Meningocele / diagnosis
  • Meningocele / surgery
  • Pneumococcal Vaccines / immunology
  • Recurrence
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Biomarkers
  • Pneumococcal Vaccines