[Progress in studies on obstructive sleep apnea and intestinal microecological balance]

Abstract

SummaryObstructive sleep apnea （OSA） is closely related to the development of various diseases. Hypoxic perfusion caused by OSA can mediate the occurrence of inflammatory reactions or aggravate metabolic disorders to affect intestinal microecological balance. Intestinal bacteria can participate in the development of inflammatory reaction or metabolic disorder by itself or its components, and the oxidative stress reaction of the body develops in a vicious circle. The mechanism has not yet been fully elucidated, so we reviewed the research progress on OSA and intestinal microecological balance.

Keywords: insulin resistance; intestinal microecology; intestinal mucosal injury; metabolic syndrome; oxidative stress response; sleep apnea, obstructive.