Epilepsy Benchmarks Area II: Prevent Epilepsy and Its Progression

Devin K Binder; Detlev Boison; Tore Eid; Wayne N Frankel; Ana Mingorance; Bret N Smith; Penny A Dacks; Vicky Whittemore; Annapurna Poduri; AES/NINDS Epilepsy Benchmarks Stewards

doi:10.1177/1535759719895274

Epilepsy Benchmarks Area II: Prevent Epilepsy and Its Progression

Epilepsy Curr. 2020 Jan-Feb;20(1_suppl):14S-22S. doi: 10.1177/1535759719895274. Epub 2020 Jan 15.

Authors

Devin K Binder¹, Detlev Boison², Tore Eid³, Wayne N Frankel⁴, Ana Mingorance⁵, Bret N Smith⁶, Penny A Dacks⁷, Vicky Whittemore⁸, Annapurna Poduri⁹; AES/NINDS Epilepsy Benchmarks Stewards

Affiliations

¹ Division of Biomedical Sciences, School of Medicine, Center for Glial-Neuronal Interactions, University of California, Riverside, CA, USA.
² Department of Neurosurgery, Robert Wood Johnson and New Jersey Medical Schools, Rutgers University, Piscataway, NJ, USA.
³ Department of Laboratory Medicine, Neurosurgery and Molecular Physiology, Yale University, New Haven, CT, USA.
⁴ Department of Genetics & Development, Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, USA.
⁵ Dracaena Consulting SL, Madrid, Spain.
⁶ Department of Neuroscience, University of Kentucky College of Medicine, Lexington, KY, USA.
⁷ American Epilepsy Society, Chicago, IL, USA.
⁸ Division of Neuroscience, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.
⁹ Epilepsy Genetics Program, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Abstract

Area II of the 2014 Epilepsy Research Benchmarks aims to establish goals for preventing the development and progression of epilepsy. In this review, we will highlight key advances in Area II since the last summary of research progress and opportunities was published in 2016. We also highlight areas of investigation that began to develop before 2016 and in which additional progress has been made more recently.

Keywords: NINDS benchmarks for epilepsy research; benchmarks; epilepsy; epilepsy prevention; epileptogenesis; preventing epilepsy; prevention clinical trials; progress in epilepsy research.

Abstract

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