The World Health Organization has proposed a 65% reduction in viral hepatitis-related mortality by 2030, and the key to achieve this ambitious goal is to reduce mortality from viral hepatitis-related hepatocellular carcinoma (HCC). HCC is the second leading cause of death in patients with malignant tumors in China. Notably, one of the important links to reduce the risk of HCC is based on HCC risk factors and very early warning HCC biomarkers. Therefore, constructing a HCC risk prediction model, accurately identifying high-risk HCC population, developing an individualized HCC screening strategy, may improve the early HCC diagnosis and cure rate in China.
世界卫生组织提出到2030年要将病毒性肝炎相关死亡下降65%，而实现这一宏伟目标的关键在于降低病毒性肝炎相关肝细胞癌（HCC）的死亡率。在我国，HCC是导致恶性肿瘤患者死亡的第二大原因。基于HCC发生危险因素和极早期预警标志物，构建HCC风险预测模型，精准识别高危HCC人群，制定个性化的HCC筛查策略，提高HCC早诊率，提升早期HCC的治愈率，是当前我国降低病毒性肝炎危害工作的重要环节之一。.
Keywords: Carcinoma, hepatocellular; Early diagnosis; Surveillance; Viral hepatitis.