Only 20-25% Deuteration of Polyunsaturated Fatty Acids Prevents Lipid Peroxidation

Trends Mol Med. 2020 Apr;26(4):351-352. doi: 10.1016/j.molmed.2020.01.002. Epub 2020 Feb 4.

Authors

Paldeep S Atwal¹, Mark Midei², Peter Milner²

Affiliations

¹ Retrotope, Inc., Los Altos, CA, USA. Electronic address: Paldeep@Retrotope.com.
² Retrotope, Inc., Los Altos, CA, USA.

PMID: 32033907
DOI: 10.1016/j.molmed.2020.01.002

No abstract available

Keywords: RT001; deuterated polyunsaturated fatty acids; kinetic isotope effect; lipid peroxidation.

Publication types

Letter
Comment

MeSH terms

Antioxidants
Drug Development
Fatty Acids, Unsaturated
Humans
Lipid Peroxidation*
Mitochondrial Diseases*

Substances

Antioxidants
Fatty Acids, Unsaturated