[Comparison between transient elastography and noninvasive diagnostic model for the evaluation of liver fibrosis in patients with liver disease of schistosoma japonicum]

Zhonghua Gan Zang Bing Za Zhi. 2020 Feb 20;28(2):163-167. doi: 10.3760/cma.j.issn.1007-3418.2020.02.013.
[Article in Chinese]

Abstract

选取73例血吸虫病患者，以肝活组织检查为"金标准" ，评估瞬时弹性诊断仪（Fibroscan）和无创诊断模型对日本血吸虫肝病患者肝纤维化程度预测价值。结果Fibroscan测定值与肝组织病理等级之间Spearman相关系数r = 0.651（P < 0.001)。Fibroscan预测F1（轻微肝纤维化）的截断值7.90；预测F2（显著肝纤维化）的截断值为8.15；预测F3（严重肝纤维化）的截断值为10.1；预测F4（肝硬化）的截断值为18.0。ARPI和FIB-4预测血吸虫病患者轻微肝纤维化具有较高价值；Fibroscan预测血吸虫病患者显著和严重肝纤维化时，优于无创诊断模型。.

Keywords: Fibroscan; Liver brosis; Noinvasive diagnosis; Schistosoma japonicum.

Publication types

  • Comparative Study

MeSH terms

  • Animals
  • Elasticity Imaging Techniques / methods*
  • Humans
  • Liver / diagnostic imaging
  • Liver Cirrhosis / diagnostic imaging*
  • Liver Cirrhosis / etiology*
  • Liver Diseases / diagnostic imaging*
  • Liver Diseases / parasitology
  • Schistosoma japonicum / isolation & purification*