The Safeguarding Microglia: Central Role for P2Y12 Receptors

The Safeguarding Microglia: Central Role for P2Y₁₂ Receptors

Front Pharmacol. 2021 Jan 14:11:627760. doi: 10.3389/fphar.2020.627760. eCollection 2020.

Si-Si Lin^{1

2}, Yong Tang^{1

2}, Peter Illes^{1

2

3}, Alexei Verkhratsky^{2

4

5}

¹ Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
² International Collaborative Center on Big Science Plan for Purine Signalling, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
³ Rudolf Boehm Institute for Pharmacology and Toxicology, University of Leipzig, Leipzig, Germany.
⁴ Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom.
⁵ Achucarro Centre for Neuroscience, IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.

No abstract available

Keywords: P2Y12 receptors; microglia; neurone-microglial crosstalk; neuroprotective; purinergic signalling.