GC-MS and Surface Characteristics of Polyvinyl Siloxane-An In Vitro Analysis

J Chromatogr Sci. 2022 Feb 16;60(2):111-116. doi: 10.1093/chromsci/bmab054.

Abstract

Objective: To assess the surface characteristics, composition and release of components of Polyvinyl siloxane (PVS) impression material and explore the use of the material other than for impressions.

Methods: Forty samples of 0.5-mm thickness and 8-mm diameter PVS discs, with few perforations, were prepared and divided into four groups. Group 1 in methanol was analyzed by GC-MS immediately and on 1st, 7th and 14th day. Group 2 and 3 placed in 10 mL of human saliva and in artificial nasal fluid, respectively, were analyzed by GC-MS at 24 hours. Group 4 was subjected to surface characteristics analysis by placing five PVS discs each in 1 mL of human saliva and 1 mL of artificial nasal fluid, respectively.

Results: On Day 1, Dodecanoic acid, methyl ester, Cyclononasiloxane, octadecamethyl, Cyclodecasiloxane and eicosamethyl (four peaks) were observed in Group 1. At 24 hours, Group 2 had additional compounds of 2-Decene,7-methyl-(Z)-, 2-Undecene,8-methyl-(Z)- and Lauryl acetate. Group 3 showed release of 32 compounds, but their retention time was less. Surface characteristics on Day 14 revealed no noticeable changes.

Conclusions: The study revealed that there was a lack of any adverse component release from PVS for a period of 2 weeks based on GC-MS analysis.

MeSH terms

  • Gas Chromatography-Mass Spectrometry
  • Humans
  • Polyvinyls*
  • Siloxanes*

Substances

  • Polyvinyls
  • Siloxanes
  • vinyl polysiloxane