Long COVID and the brain network of Proust's madeleine: targeting the olfactory pathway

Eric Guedj; Françoise Lazarini; Silvia Morbelli; Mathieu Ceccaldi; Charlotte Hautefort; Aurélie Kas; Thomas Radulesco; Dominique Salmon-Ceron; Carole Eldin

doi:10.1016/j.cmi.2021.05.015

Long COVID and the brain network of Proust's madeleine: targeting the olfactory pathway

Clin Microbiol Infect. 2021 Sep;27(9):1196-1198. doi: 10.1016/j.cmi.2021.05.015. Epub 2021 May 17.

Authors

Eric Guedj¹, Françoise Lazarini², Silvia Morbelli³, Mathieu Ceccaldi⁴, Charlotte Hautefort⁵, Aurélie Kas⁶, Thomas Radulesco⁷, Dominique Salmon-Ceron⁸, Carole Eldin⁹

Affiliations

¹ Aix Marseille Université, APHM, CNRS, Centrale Marseille, Institut Fresnel, Timone Hospital, CERIMED, Nuclear Medicine Department, Marseille, France. Electronic address: eric.guedj@ap-hm.fr.
² Institut Pasteur, Perception and Memory Unit, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 3571, Paris, France.
³ IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
⁴ Aix Marseille Université, INSERM, Inst Neurosci Syst, & APHM, Service de Neurologie et de Neuropsychologie, CHU Timone, Marseille, France.
⁵ Department of Otorhinolaryngology, Lariboisière Hospital, Assistance Publique - Hôpitaux de Paris, INSERM U1141, Université de Paris, Paris, France.
⁶ APHP Sorbonne Université, Nuclear Medicine Department, CNRS, INSERM, LIB, Paris, France.
⁷ Aix-Marseille Université, APHM, IUSTI, La Conception University Hospital, Department of Oto-Rhino-Laryngology Head and Neck Surgery, Marseille, France.
⁸ Department of Infectious Medicine and Immunology, Hotel Dieu Hospital, Assistance Publique-Hôpitaux de Paris, University of Paris, Paris, France.
⁹ Aix Marseille Université, IRD, AP-HM, SSA, VITROME, IHU-Méditerranée Infection, Marseille, France.

No abstract available

Keywords: Anosmia; Complaints; Coronavirus disease 2019; Emotion; Memory; Olfaction; Positron emission tomography; Rehabilitation; Severe acute respiratory syndrome coronavirus 2; [(18)F]fluorodeoxyglucose.

MeSH terms

COVID-19 / complications*
COVID-19 / diagnostic imaging
COVID-19 / metabolism
Fluorodeoxyglucose F18
Humans
Memory Disorders / virology
Olfaction Disorders / diagnostic imaging*
Olfaction Disorders / virology*
Olfactory Bulb / diagnostic imaging*
Olfactory Bulb / metabolism
Positron-Emission Tomography
Post-Acute COVID-19 Syndrome
Radiopharmaceuticals

Substances

Radiopharmaceuticals
Fluorodeoxyglucose F18